Senior Research Nurse | The Christie NHS Foundation Trust


Company:	The Christie NHS Foundation Trust
Salary:	£49,387 - £56,515 Per annum, Pro rata
Hours:	Full-time
Location:	Manchester, M20 4BX
Job type:	Permanent
Posting date:	25 Sept 2026
Closing date:	25 Oct 2026

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Summary

This is an exciting opportunity for a highly motivated Research Nurse to join the Advanced Immune and Cell Therapy (AICT) Research Team. The AICT team is an early phase clinical trials team specialising in the delivery of cell therapy studies and complex immunotherapy trials across a range of solid cancer types. The team strives to deliver the next generation of innovative cancer treatments for solid tumors.

Examples of our cell therapy studies include CAR-T, TIL and TCR trials.

The band 7 Clinical Research Nurse is expected to provide leadership of the AICT Research team and manage a varied and growing portfolio of early phase oncology studies.

Central to this role is the responsibility of assessing and managing the care pathways including the delivery of all specified treatments for participants in research within a multidisciplinary team. Key responsibilities of the post include the co-ordination of the cell therapy and complex immunotherapy trial protocols and providing support for early phase solid tumour trial patients.

The Band 7 Clinical Research Nurse will use their role to enhance the team’s ability and capacity to undertake high quality clinical research by developing knowledge, skills, and practice within the team.

A background in research and oncology, flexibility in working, excellent communication and interpersonal skills are essential.

The Band 7 Clinical Research Nurse will be involved in every stage of the portfolio activities including feasibility reviews of new clinical trial opportunities, set-up and activation of new trials, patient recruitment and management, supporting team with data query resolution, reviewing protocol amendments, providing patient-centred insights to the research delivery team by supporting both the patients and the team through all aspects of clinical research of the AICT portfolio.

With support from the team the Band 7 Clinical Research Nurse will ensure that the safety and wellbeing of the patients is maintained within the requirement of the multi-regulatory frameworks for clinical research ensuring compliance with ICH/GCP standards and Trust SOPs.

They will provide support, induction, continued supervision and management of the AICT research team and Demonstrate awareness and contribution to divisional, Trust and national objectives and strategies.

By utilising national frameworks for auditing patients experience the Band 7 Clinical Research Nurse will ensure the patients participating in AICT portfolio studies will have the best possible experience whilst participating in clinical research.

They will raise the profile of the clinical research nurse and clinical trials within the trust by engaging in promotional events relating to clinical research with attendance and contributions at local, national and international meetings.

The Christie is one of Europe’s leading cancer centres, looking after more than 64,000 patients a year. We are based in Manchester and serve a population of 3.2 million across Greater Manchester & Cheshire, but as a national specialist around 25% patients are referred to us from other parts of the country.

We are the largest radiotherapy provider in the NHS with one in 20 treatments delivered at The Christie. We have up to 15 linear accelerators operating across our network of sites. We operate the largest chemotherapy unit in the UK on our main site and treatments are also provided at 13 other networked sites, and in patients homes. And as a specialist tertiary surgical centre, we focus on rare cancers, complex procedures, and multidisciplinary approaches to cancer surgery, specialising in colorectal, peritoneal, gynaecological, urological and plastic surgery.

We are also an international leader in research, with world first breakthroughs for over 100 years. We have been named by the UK’s National Institute for Health Research (NIHR), as one of the best hospitals providing opportunities for patients to participate in clinical research studies, with more than 800 studies open at any time, caring for over 3,000 patients.

Clinical Research Co-ordination

• Work autonomously in all areas of practice relating to clinical research.

• Understand and deliver care in accordance with regulatory approved clinical research protocols.

• Oversee the process for obtaining NHS permissions (R&D approval) for clinical trials within team. As project lead, ensures permissions are in place prior to any patient recruitment.

• Undertake feasibility and risk assessments of clinical trial protocols in conjunction with Team Leader, Principal Investigator and Senior Clinical Trials Co-Ordinator

• Ensure all clinical trial activities are recorded in appropriate systems in a timely manner.

• Awareness of trial specific, regional, and national targets.

• Initiate new recruitment strategies for recruiting patients to clinical trials including engagement with the research network.

• In conjunction with Team Leader lead on the delegation of all trial related activities to research team members (clinical and administrative) and ensure compliance with SOPs and ICH/GCP.

• Work with team leader and sponsor companies in the preparation and negotiation of financial contracts for individual trials.

• Arrange and facilitate clinical trial related meetings.

• In conjunction with Team Leader, oversee appropriate financial remunerations for clinical trial activity

Clinical Service and Professional Responsibilities

• Assimilation of highly complex information relating to clinical trials and communication to patients at a level appropriate to their understanding. Ensure highly sensitive information is communicated to patients, relatives, and careers regarding prognosis

• Responsible for the development, implementation, and review of specialist care pathways in conjunction with appropriate personnel.

• Demonstration of expert knowledge in specialist area to maintain clinical excellence.

• Set up processes/patient pathways in conjunction with appropriate personnel from specialist research areas to promote a cost-effective timely service for individual protocols (shared care pathways, specialist clinics, etc.).

• Support Team Leader in delivering divisional and trust strategic objectives including performance indicators and metrics.

• Escalation of governance issues impacting on delivery of job purpose.

• To act as a primary contact point for the clinical trial patients and act as adviser to other health care professionals.

• Responsibility for maintenance and development of professional knowledge and practice by attending mandatory and specialist training (e.g., GCP) in accordance with local policy

• Ensuring care delivery standards in accordance with trial protocol, local policy, NMC Code of Practice Conduct and current best practice

• Development and maintenance of a high-quality service by:

o Overseeing the safe administration of all licensed and unlicensed medicinal products within the context of a clinical trial.

o Overseeing assessment and evaluation of treatment toxicities and initiation of appropriate intervention.

o Contribute to development of specialist Standard Operating Procedures and guidelines

• Provide education and support for non-research staff in the delivery of protocol driven treatment for all patients.

• Participate in monitoring and audit activities within research team

• To carry out non-medical prescribing within scope of professional practice and in accordance with local policies and procedures and national legislation (optional and depending on clinical service needs).

Personal Education, Training and Development

• Maintain professional development whilst evaluating own specialist knowledge and practice through a process of appraisal and personal development planning.

• Promote the role of the clinical research nurse as an integral part of the healthcare system.

• Increase and maintain awareness of current advances in cancer treatments, research and nursing practice thereby maintaining the highest standard of care for patients with cancer and implementing evidence-based care by continuing professional development.

• Participation in trust-wide education programs and study days.

• Obtain clinical supervision as appropriate.

• To keep up to date with departmental, Trust, UK and EU developments for the management of clinical research ensuring timely, effective implementation of changes.

• Attendance at team and divisional meetings.

Staff Management and Development

• In conjunction with the team leader, provide the induction, continued supervision and management of the research teams.

• In conjunction with the team leader, be responsible for ensuring all members of the research nurse team undergo regular appraisal and support appropriate training and development opportunities in line with role requirements.

• Lead on the development of specialist study days within own research team

• Provide specialist education and training in relation to clinical trials to all key stakeholders.

• Disseminate information by attendance and /or presentations at local, national and international conferences/meetings

• Be responsible for the development of members of the research team.

EU DIRECTIVE ICH/GCP

All personnel involved in clinical research have a responsibility to ensure that clinical trials are conducted in accordance with the EU Directive and ICH/GCP.

This advert closes on Friday 9 Oct 2026

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