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Postdoctoral Research Scientist - Brain Tumour Research

Company:University of Oxford
Salary:£39,424 to £53,483 a year
Hours:Full-time
Location:Oxford, OX3 7DQ
Working pattern:On-site
Job type:Contract
Posting date:9 Sept 2026
Closing date:9 Oct 2026
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Summary

We are seeking to appoint a Postdoctoral Research Scientist to join the Pathania Laboratory at the Ludwig Institute for Cancer Research. Working with Dr Manav Pathania, the postholder will contribute to the development of disease-representative models of brain tumours, with a particular focus on ependymoma and atypical teratoid/rhabdoid tumours, to identify precision therapy opportunities, tumour-microenvironment interactions and mechanisms of treatment resistance.

We take a multidisciplinary approach, integrating in vivo models, primary and patient-derived cell lines, drug and CRISPR screening, cell and molecular biology, biochemistry, immunology, genomics and computational biology, to address fundamental questions underlying brain tumour biology. We rely on established collaborations with researchers locally and around the world and promote a cooperative and supportive research environment— encouraging independence, self-reliance and the development of synergistic, mutually beneficial interactions between lab members and a communal team spirit. We offer access to state-of-the-art core facilities, and everything needed for ambitious projects to have a chance at success, as well as support for training and networking opportunities.

Reporting to Manav Pathania, the Postdoctoral Research Scientist recruited to this role will function as a senior member of the group working across multiple projects as well as supervising and mentoring other lab members to open up new avenues of research within the lab. They will focus on developing new models of ependymoma and atypical teratoid/rhabdoid tumours, and on using these to identify new precision therapy opportunities, tractable microenvironmental interactions, and resistance mechanisms using approaches the lab has previously developed.

You will be responsible for designing and conducting high-quality independent research, analysing and presenting experimental data, and managing research activities across multiple projects. The role includes supervising and training junior researchers in in vivo and in vitro techniques. You will also contribute to new research ideas, grant applications and publications, and collaboration with colleagues across multidisciplinary research programmes.

Applications for this vacancy should be made online and you will need to upload a supporting statement and CV. Your supporting statement must explain how you meet each of the selection criteria for the post using examples of your skills and experience. Please restrict your documentation to your CV and supporting statement only. Any other documents will be requested at a later date.

This position is offered full time on a fixed term contract until 31 December 2029 and is funded by Ludwig.

Only applications received before 12 midday on 9th October 2026 will be considered. Please quote 188517 on all correspondence.

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