Research Assistant - cell biologist in Parkinson’s
| Company: | University of Oxford |
|---|---|
| Salary: | £35,681 - £41,636 |
| Hours: | Full-time |
| Location: | Oxford, OX1 3QU |
| Working pattern: | On-site |
| Job type: | Contract |
| Posting date: | 25 Aug 2026 |
| Closing date: | 18 Sept 2026 |
Summary
Overview of the role:
We are seeking a Research Assistant neuronal cell biologist to join the Wade-Martins Laboratory at the Kavli Institute of Nanoscience Discovery within DPAG. The ideal candidate will be a neuronal cell biologist with experience working in neuronal models of neurodegeneration, ideally in human stem cell-derived models, and a good knowledge of Parkinson’s disease. This is an exciting collaborative opportunity to contribute to the development of a novel therapeutic approach for Parkinson’s, a major age-related neurodegenerative disease, at the interface between academic research and target and drug discovery using state-of-the-art human stem cell-derived neuronal models.
In this role, you will undertake differentiation of iPSC-dopamine neurons from Parkinson’s patients and controls and applying cellular and molecular techniques to probe endolysosomal and mitochondrial biology, including metabolic and lipidomic profiling, to validate a novel therapeutic target. This post is available immediately for two years.
Key responsibilities:
• Undertake the differentiation of iPSC-dopamine neurons from Parkinson’s patients and controls and apply cellular and molecular techniques to probe endolysosomal and mitochondrial biology
• Undertake analysis of the phenotypic effect of pharmacological inhibitors on cell biology phenotypes in cellular models of Parkinson’s
• Undertake metabolic and lipidomic profiling in iPSC-dopamine neurons to look at relevant biological pathways
• Contribute to wider project planning, including ideas for new research projects
• Determine the most appropriate methodologies to test hypotheses, and identify suitable alternatives if technical problems arise
• Select, follow, and adapt experimental protocols
• Gather, analyse, and present scientific data from a variety of sources
• Contribute to scientific reports and journal articles and the presentation of data/papers at conferences
• Manage own research and administrative activities, within guidelines provided by senior colleagues
• Collaborate effectively with other team members to achieve collective goals
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